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1

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Amsterdam, Netherlands (Sunday 1 July 2012)] Space Telescopes and Instrumentation 2012: Optical, Infrared, and Millimeter Wave - MOIRE: initial demonstration of a transmissive diffractive membrane optic for large lightweight optical telescopes

Atcheson, Paul D., Stewart, Chris, Domber, Jeanette, Whiteaker, Kevin, Cole, Jerold, Spuhler, Peter, Seltzer, Aaron, Britten, Jerald A., Dixit, Shamasundar N., Farmer, Brandon, Smith, Lensey, Clampin,

Année:

2012

Langue:

english

Fichier:

PDF, 9.16 MB

english, 2012

2

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Montréal, Quebec, Canada (Sunday 22 June 2014)] Space Telescopes and Instrumentation 2014: Optical, Infrared, and Millimeter Wave - MOIRE: ground demonstration of a large aperture diffractive transmissive telescope

Oschmann, Jacobus M., Clampin, Mark, Fazio, Giovanni G., MacEwen, Howard A., Atcheson, Paul, Domber, Jeanette, Whiteaker, Kevin, Britten, Jerald A., Dixit, Shamasundar N., Farmer, Brandon

Année:

2014

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2014

3

Cocaine Directly Inhibits α6-Containing Nicotinic Acetylcholine Receptors in Human SH-EP1 Cells and Mouse VTA DA Neurons

Chen, Dejie, Gao, Fenfei, Ma, Xiaokuang, Eaton, Jason Brek, Huang, Yuanbing, Gao, Ming, Chang, Yongchang, Ma, Zegang, Der-Ghazarian, Taleen, Neisewander, Janet, Whiteaker, Paul, Wu, Jie, Su, Quanxi

Journal:

Frontiers in Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2019

4

Immunolabeling demonstrates the interdependence of mouse brain α4 and β2 nicotinic acetylcholine receptor subunit expression

Paul Whiteaker, John F. Cooper, Outi Salminen, Michael J. Marks, Tristan D. Mcclure-Begley, Robert W.B. Brown, Allan C. Collins, Jon M. Lindstrom

Journal:

The Journal of Comparative Neurology

Année:

2006

Langue:

english

Fichier:

PDF, 10.60 MB

english, 2006

5

Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6∗ subtype

Scott R. Breining, Merouane Bencherif, Sharon R. Grady, Paul Whiteaker, Michael J. Marks, Charles R. Wageman, Henry A. Lester, Daniel Yohannes

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 471 KB

english, 2009

6

An autoradiographic study of the distribution of binding sites for the novel α7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain

Paul Whiteaker, Andrew R. L. Davies, Michael J. Marks, Ian S. Blagbrough, Barry V. L. Potter, Adrian J. Wolstenholme, Allan C. Collins, Susan Wonnacott

Journal:

European Journal of Neuroscience

Année:

1999

Langue:

english

Fichier:

PDF, 413 KB

english, 1999

7

Characterization of [125I]epibatidine binding and nicotinic agonist-mediated 86Rb+ efflux in interpeduncular nucleus and inferior colliculus of β2 null mutant mice

Michael J. Marks, Paul Whiteaker, Sharon R. Grady, Marina R. Picciotto, J. Michael McIntosh, Allan C. Collins

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 680 KB

english, 2002

8

John Daly’s Compound, Epibatidine, Facilitates Identification of Nicotinic Receptor Subtypes

Michael J. Marks, Duncan S. Laverty, Paul Whiteaker, Outi Salminen, Sharon R. Grady, J. Michael McIntosh, Allan C. Collins

Journal:

Journal of Molecular Neuroscience

Année:

2010

Langue:

english

Fichier:

PDF, 368 KB

english, 2010

9

Nicotinic α5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers

Robert W. B. Brown, Allan C. Collins, Jon M. Lindstrom, Paul Whiteaker

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 242 KB

english, 2007

10

U18666A, a cholesterol-inhibition agent, modulates human neuronal nicotinic acetylcholine receptors heterologously expressed in SH-EP1 cell line

Chao Zheng, Meng-Ya Wang, Qiang Liu, Makoto Wakui, Paul Whiteaker, Ronald J. Lukas, Jie Wu

Journal:

Journal of Neurochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 604 KB

english, 2009

11

Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling α7 nicotinic acetylcholine receptors

Arik J. Hone, Paul Whiteaker, Jesse L. Mohn, Michele H. Jacob, J. Michael McIntosh

Journal:

Journal of Neurochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 690 KB

english, 2010

12

Pharmacological and immunochemical characterization of α2* nicotinic acetylcholine receptors (nAChRs) in mouse brain

Brown, Robert WB, Brennan, Robert J, Collins, Allan C, Lindstrom, Jon M, Wilking, Jennifer A, Boulter, Jim, Whiteaker, Paul

Journal:

Acta Pharmacologica Sinica

Année:

2009

Langue:

english

Fichier:

PDF, 377 KB

english, 2009

13

Nicotinic acetylcholine receptor α7 subunits with a C2 cytoplasmic loop yellow fluorescent protein insertion form functional receptors

Murray, Teresa A, Liu, Qiang, Whiteaker, Paul, Wu, Jie, Lukas, Ronald J

Journal:

Acta Pharmacologica Sinica

Année:

2009

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2009

14

Identification of a novel nicotinic binding site in mouse brain using [125I]-epibatidine

Paul Whiteaker, Melissa Jimenez, J Michael McIntosh, Allan C Collins, Michael J Marks

Journal:

British Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 341 KB

english, 2000

15

A novel fluorescent α-conotoxin for the study of α7 nicotinic acetylcholine receptors

Arik J. Hone, Paul Whiteaker, Sean Christensen, Yingxian Xiao, Erin L. Meyer, J. Michael McIntosh

Journal:

Journal of Neurochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 439 KB

english, 2009

16

The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum

Sharon R. Grady, Outi Salminen, Duncan C. Laverty, Paul Whiteaker, J. Michael McIntosh, Allan C. Collins, Michael J. Marks

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

17

Labeling α7 nAChRs on hippocampal neurons using fluorescent analogs of α-conotoxin ArIB[V11L;V16A]

Arik J. Hone, Jesse L. Mohn, Michele Jacob, Paul Whiteaker, J. Michael McIntosh

Journal:

Biochemical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2009

18

Gain of function mutants in human or mouse nAChR β3 subunits interchangeably activate either human or mouse α6β4-nAChR, but not human or mouse α6β2-nAChR

Bhagirathi Dash, Minoti Bhakta, Paul Whiteaker, Jerry A. Stizel, Yongchang Chang, Ronald J. Lukas

Journal:

Biochemical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 77 KB

english, 2009

19

Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors

Sharon R. Letchworth, Paul Whiteaker

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 540 KB

english, 2011

20

Comparison of binding and functional activity profiles for a set of nicotinic acetylcholine receptor ligands across multiple α6* expression systems

Scott R. Breining, Christopher Hepler, Paul Whiteaker, Maryka Quik, Sharon R. Grady, Daniel Yohannes

Journal:

Biochemical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 55 KB

english, 2011

21

Characterization of human urinary bladder KATP channels containing SUR2B splice variants expressed in L-cells

Victoria E Scott, Rachel A Davis-Taber, Christopher Silvia, Lisa Hoogenboom, Won Choi, Paul Kroeger, Kristi L Whiteaker, Murali Gopalakrishnan

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 496 KB

english, 2004

22

Pharmacological and null mutation approaches reveal nicotinic receptor diversity

Paul Whiteaker, Michael J Marks, Sharon R Grady, Ying Lu, Marina R Picciotto, Jean-Pierre Changeux, Allan C Collins

Journal:

European Journal of Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 577 KB

english, 2000

23

A novel α-conotoxin MII-sensitive nicotinic acetylcholine receptor modulates [3H]-GABA release in the superficial layers of the mouse superior colliculus

Tristan D. McClure-Begley, Charles R. Wageman, Sharon R. Grady, Michael J. Marks, J. Michael McIntosh, Allan C. Collins, Paul Whiteaker

Journal:

Journal of Neurochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 375 KB

english, 2012

24

Attenuation of CNS inflammatory responses by nicotine involves α7 and non-α7 nicotinic receptors

Junwei Hao, Alain R. Simard, Gregory H. Turner, Jie Wu, Paul Whiteaker, Ronald J. Lukas, Fu-Dong Shi

Journal:

Experimental Neurology

Année:

2011

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2011

25

In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity α6∗ Nicotinic Acetylcholine Receptors

Ryan M. Drenan, Sharon R. Grady, Paul Whiteaker, Tristan McClure-Begley, Sheri McKinney, Julie M. Miwa, Sujata Bupp, Nathaniel Heintz, J. Michael McIntosh, Merouane Bencherif, Michael J. Marks, Henry

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2008

26

The subunit composition and pharmacology of α-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay

Outi Salminen, Paul Whiteaker, Sharon R. Grady, Allan C. Collins, J. Michael McIntosh, Michael J. Marks

Journal:

Neuropharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 301 KB

english, 2005

27

Structural differences determine the relative selectivity of nicotinic compounds for native α4β2-, α6β2-, α3β4*- and α7-nicotine acetylcholine receptors

Sharon R. Grady, Ryan M. Drenan, Scott R. Breining, Daniel Yohannes, Charles R. Wageman, Nikolai B. Fedorov, Sheri McKinney, Paul Whiteaker, Merouane Bencherif, Henry A. Lester, Michael J. Marks

Journal:

Neuropharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 620 KB

english, 2010

28

A component of Premarin® enhances multiple cognitive functions and influences nicotinic receptor expression

Joshua S. Talboom, Elizabeth B. Engler-Chiurazzi, Paul Whiteaker, Alain R. Simard, Ronald Lukas, Jazmin I. Acosta, Laszlo Prokai, Heather A. Bimonte-Nelson

Journal:

Hormones and Behavior

Année:

2010

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2010

29

Chemistry, Pharmacology, and Behavioral Studies Identify Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part II

Zhang, Han-Kun, Yu, Li-Fang, Eaton, J. Brek, Whiteaker, Paul, Onajole, Oluseye K., Hanania, Taleen, Brunner, Daniela, Lukas, Ronald J., Kozikowski, Alan P.

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 461 KB

english, 2013

30

Nicotine–morphine interactions at α4β2, α7 and α3⁎ nicotinic acetylcholine receptors

Talka, Reeta, Salminen, Outi, Whiteaker, Paul, Lukas, Ronald J., Tuominen, Raimo K.

Journal:

European Journal of Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 871 KB

english, 2013

31

α6β2-subtype nicotinic acetylcholine receptors are more sensitive than α4β2-subtype receptors to regulation by chronic nicotine administration

Marks, Michael J., Grady, Sharon R., Salminen, Outi, Paley, Miranda A., Wageman, Charles R., McIntosh, J. Michael, Whiteaker, Paul

Journal:

Journal of Neurochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 529 KB

english, 2014

32

α7 nicotinic acetylcholine receptors contribute to amyloid-induced neuronal hyperexcitation

Wu, Jie, Liu, Qiang, Whiteaker, Paul, Lukas, Ronald J.

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 45 KB

english, 2010

33

Discovery, Synthesis, and Structure Activity of a Highly Selective α7 Nicotinic Acetylcholine Receptor Antagonist †

Whiteaker, Paul, Christensen, Sean, Yoshikami, Doju, Dowell, Cheryl, Watkins, Maren, Gulyas, Jozsef, Rivier, Jean, Olivera, Baldomero M., McIntosh, J. Michael

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 134 KB

english, 2007

34

The Resistome of Pseudomonas aeruginosa in Relationship to Phenotypic Susceptibility

Kos, Veronica N., Déraspe, Maxime, McLaughlin, Robert E., Whiteaker, James D., Roy, Paul H., Alm, Richard A., Corbeil, Jacques, Gardner, Humphrey

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2015

35

The potent and selective α 4 β 2/ α 6-nicotinic acetylcholine receptor partial agonist 2-[5-[5-(( S )Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile

Yu, Li-Fang, Brek Eaton, J., Zhang, Han-Kun, Sabath, Emily, Hanania, Taleen, Li, Guan-Nan, van Breemen, Richard B., Whiteaker, Paul, Liu, Qiang, Wu, Jie, Chang, Yong-Chang, Lukas, Ronald J., Brunner,

Journal:

Pharmacology Research & Perspectives

Année:

2014

Langue:

english

Fichier:

PDF, 723 KB

english, 2014

36

Small-Molecule Inhibitors of Gram-Negative Lipoprotein Trafficking Discovered by Phenotypic Screening

McLeod, Sarah M., Fleming, Paul R., MacCormack, Kathleen, McLaughlin, Robert E., Whiteaker, James D., Narita, Shin-ichiro, Mori, Makiko, Tokuda, Hajime, Miller, Alita A., DiRita, V. J.

Journal:

Journal of Bacteriology

Année:

2015

Langue:

english

Fichier:

PDF, 3.32 MB

english, 2015

37

Assessing Bias in Experiment Design for Large Scale Mass Spectrometry-based Quantitative Proteomics

Prakash, A., Piening, B., Whiteaker, J., Zhang, H., Shaffer, S. A., Martin, D., Hohmann, L., Cooke, K., Olson, J. M., Hansen, S., Flory, M. R., Lee, H., Watts, J., Goodlett, D. R., Aebersold, R., Paul

Journal:

Molecular & Cellular Proteomics

Année:

2007

Langue:

english

Fichier:

PDF, 341 KB

english, 2007

38

Differential modulation of EAE by α9- and β2-nicotinic acetylcholine receptors

Simard, Alain R, Gan, Yan, St-Pierre, Stéphanie, Kousari, Ariana, Patel, Varun, Whiteaker, Paul, Morley, Barbara J, Lukas, Ronald J, Shi, Fu-Dong

Journal:

Immunology & Cell Biology

Année:

2013

Langue:

english

Fichier:

PDF, 646 KB

english, 2013

39

Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy

Weltzin, Maegan M., Lindstrom, Jon M., Lukas, Ronald J., Whiteaker, Paul

Journal:

Neuropharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2016

40

Differential α4(+)/(-)β2 Agonist Binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function Within and Between Isoforms.

Lucero, Linda M., Weltzin, Maegan M., Eaton, J. Brek, Cooper, John F., Lindstrom, Jon M., Lukas, Ronald J., Whiteaker, Paul

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2015

41

Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain

Wu, Jie, Liu, Qiang, Tang, Pei, Mikkelsen, Jens D., Shen, Jianxin, Whiteaker, Paul, Yakel, Jerrel L.

Journal:

Trends in Pharmacological Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2016

42

Development and validation of an α3β4 nicotinic acetylcholine receptor (nAChR) high-throughput screening- (HTS-) ready assay

Whiteaker, Paul, Kassner, Michelle, Eaton, J. Brek, Petit, Joachim, Meurice, Nathalie, Yin, Holly

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 328 KB

english, 2015

43

Nocturnal frontal lobe epilepsy-associated intracellular-loop mutant subunits alter single-channel properties of α4β2-nicotinic receptor isoforms

Weltzin, Maegan M., George, Andrew A., Lukas, Ronald J., Whiteaker, Paul

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 195 KB

english, 2015

44

Diverse nicotinic mechanisms in a model of multiple sclerosis

Lukas, Ronald J., Liu, Qiang, Lucero, Linda, Simard, Alain R., Whiteaker, Paul, Morley, Barbara J., Shi, Fu-Dong

Journal:

Biochemical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 301 KB

english, 2015

45

Pharmacology of nicotinic acetylcholine receptor (nAChR) upregulation in the transfected cell line, M10

WHITEAKER, PAUL, SHARPLES, CHRISTOPHER G. V., WONNACOTT, SUSAN

Journal:

Biochemical Society Transactions

Année:

1997

Langue:

english

Fichier:

PDF, 100 KB

english, 1997

46

Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1

George, Andrew A., Bloy, Abigail, Miwa, Julie M., Lindstrom, Jon M., Lukas, Ronald J., Whiteaker, Paul

Journal:

The FASEB Journal

Année:

2017

Langue:

english

Fichier:

PDF, 5.13 MB

english, 2017

47

Mechanism of Allosteric Modulation of the Cys-loop Receptors

Chang, Yongchang, Huang, Yao, Whiteaker, Paul

Journal:

Pharmaceuticals

Année:

2010

Langue:

english

Fichier:

PDF, 522 KB

english, 2010

48

Commentary: Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice

Morley, Barbara J., Whiteaker, Paul, Elgoyhen, Ana B.

Journal:

Frontiers in Cellular Neuroscience

Année:

2018

Langue:

english

Fichier:

PDF, 270 KB

english, 2018

49

Distinctive Roles for α7- and α9-Nicotinic Acetylcholine Receptors in Inflammatory and Autoimmune Responses in the Murine Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Liu, Qiang, Whiteaker, Paul, Morley, Barbara J., Shi, Fu-Dong, Lukas, Ronald J.

Journal:

Frontiers in Cellular Neuroscience

Année:

2017

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2017

50

PeIA-5466: A novel peptide antagonist containing non-natural amino acids that selectively targets α3β2 nicotinic acetylcholine receptors

Hone, Arik, Fisher, Fernando, Christensen, Sean, Gajewiak, Joanna, Larkin, David, Whiteaker, Paul, McIntosh, J. Michael

Journal:

Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2019